It may be remembered that after my marriage, and my subsequent start in private practice, the very intimate relations which had existed between Holmes and myself became to some extent modified. He still came to me from time to time when he desired a companion in his investigations, but these occasions grew more and more seldom, until I find that in the year 1890 there were only three cases of which I retain any record. During the winter of that year and the early spring of 1891, I saw in the papers that he had been engaged by the French government upon a matter of supreme importance, and I received two notes from Holmes, dated from Narbonne and from Nimes, from which I gathered that his stay in France was likely to be a long one. It was with some surprise, therefore, that I saw him walk into my consulting-room upon the evening of April 24th. It struck me that he was looking even paler and thinner than usual.